Assessing the risk from a use(s) of a substance to human health and/or the environment arising from those uses for which authorisation is being sought.

Evaluating as to whether the restrictions suggested by a Member State or the European Chemicals Agency for a substance are appropriately reducing the risk to human health and/or the environment

Evaluating proposals from Member States for harmonised classification and labelling of a substance as carcinogenic, mutagenic or toxic for reproduction category 1, 2 or 3, or as a respiratory sensitiser, or also for other effects on a case-by-case basis